The factor structure of the Concussion Clinical Profiles Screen (CP Screen) has not been empirically evaluated. In this study, 323 patients (59% male; 74% sport-related) completed CP Screen, ImPACT, and Vestibular/Ocular-Motor Screening (VOMS) at initial clinical visit within 30鈥塪ays of concussion (M鈥�=鈥�7.58卤/-6.10鈥塪ays). A second-order model best fit the data, with cognitive-fatigue, migraine, and ocular factors comprising a second-order factor. Loadings were all significant/substantial. Vestibular, ocular, and cognitive-fatigue factors all significantly ( 尾s 鈥�=鈥�.15-.44 ps鈥� 鈮� 鈥�.01) predicted assessments in similar domains, supporting concurrent validity. This study provides initial psychometric support for the structure of the CP-screen.