Article Document Academic Article Information Content Entity Continuant Continuant Journal Article Entity Entity Generically Dependent Continuant 2025-05-06T18:07:03 RDF description of Listeria rhomboencephalitis in a patient on a tumor necrosis factor alpha inhibitor (etanercept) - http://repository.healthpartners.com/individual/document-rn7016 Drugs and Drug Therapy Listeria rhomboencephalitis in a patient on a tumor necrosis factor alpha inhibitor (etanercept) Infectious Diseases Journal of Clinical Rheumatology Arthritis 20 public <p>We describe a case of an 87-year-old woman with rheumatoid arthritis on etanercept who developed subacute encephalopathy. Magnetic resonance imaging and blood cultures led to the diagnosis of Listeria monocytogenes rhomboencephalitis, which proved to be fatal. Postmortem examination of the brain revealed abscesses with extensive necrosis. Gram stain showed small gram-positive rods in the necrotic tissue and the wall lining the abscesses. While rhomboencephalitis is a rare entity, and clinical recognition may be hampered by immunosuppression such as in this case, early blood cultures, lumbar puncture, and empiric treatment with ampicillin should be initiated in all patients with suspected rhomboencephalitis if suggested by imaging and by a clinical concern for infection.<p> 2022-02-21T22:48:57.408-06:00 19972 document-rn7016 6 10.1097/RHU.0000000000000151 12696