Article Document Academic Article Information Content Entity Continuant Continuant Journal Article Entity Entity Generically Dependent Continuant 2025-06-26T09:27:29 RDF description of Incident ocular inflammation after COVID-19 infection in a US veteran population - http://repository.healthpartners.com/individual/document-rn38126 9 32 <p>PURPOSE: To investigate whether COVID-19 infection is a risk factor for incident ocular inflammatory disease. DESIGN: Retrospective case-crossover study. METHODS: The US Veterans Health Administration Corporate Data Warehouse was used to identify patients with positive COVID-19 testing and incident ocular inflammatory disease between March 2020 and May 2022. The timing of incident ocular inflammation and COVID-19 testing was assessed for each participant to determine whether positive COVID-19 testing occurred 0-60 days prior to incident ocular inflammation diagnosis (risk period) or 15-75 days after incident ocular inflammation diagnosis (control period). The main outcome measure was the odds of positive COVID-19 testing in the risk period versus control period. RESULTS: Of the 1006 patients with incident ocular inflammation and a positive COVID-19 test in the study period, the age mean ± standard deviation was 62.6 ±�9.8 years and 840 (83%) were male. The odds of COVID-19 exposure was higher in the risk than control period (odds ratio [OR], 1.56; 95% confidence interval [CI], 1.04-2.36; P�=�0.03). Ocular inflammation was more likely to be bilateral in the risk period (OR, 3.97; 95% CI, 1.01-23.01; P�=�0.03). Other ocular features and demographic characteristics were similar in the risk and control periods. Most cases of ocular inflammation were quiescent at the most recent eye examination. CONCLUSIONS: Incident ocular inflammation is associated with COVID-19 infection, but the increased risk is small, and the ocular inflammation is typically acute.<p> Incident ocular inflammation after COVID-19 infection in a US veteran population Coronavirus Infections 2024-10-31T23:13:42.423-05:00 Risk Factors COVID-19 document-rn38126 public Retrospective Studies 23072 39784 10.1080/09273948.2023.2296035 Ocular Immunology and Inflammation Eye Diseases