Article Document Academic Article Information Content Entity Continuant Continuant Journal Article Entity Entity Generically Dependent Continuant 2025-05-06T14:32:25 RDF description of Marked inflammation in catastrophic longitudinal myelitis associated with systemic lupus erythematosus - http://repository.healthpartners.com/individual/document-rn37745 16 Skin Diseases Lupus <p>Catastrophic longitudinal myelitis is an extremely rare neurologic manifestation of collagen vascular disease, described heretofore in 11 cases of SLE and 1 of Sjogren's Syndrome. This report documents markedly abnormal and worsening CSF findings on sequential CSF examinations over a period of three days (WBC >1500 cells/muL, >80% neutrophils, markedly elevated protein, and extremely low glucose levels) in the absence of infection. These abnormalities cleared rapidly with institution of immunosuppressive therapy so that a third CSF exam done within three days revealed almost complete normalization of CSF values. These findings suggest that in some cases of CLM a strong inflammatory component may be present, while in others, other pathogenic factors may predominate.<p> 23134 2024-10-31T23:13:42.423-05:00 public 10 Marked inflammation in catastrophic longitudinal myelitis associated with systemic lupus erythematosus 39908 document-rn37745