Article Document Academic Article Information Content Entity Continuant Continuant Journal Article Entity Entity Generically Dependent Continuant 2025-06-23T23:34:18 RDF description of Marked inflammation in catastrophic longitudinal myelitis associated with systemic lupus erythematosus - http://repository.healthpartners.com/individual/document-rn35384 16 22168 2024-03-31T21:00:31.442-05:00 Marked inflammation in catastrophic longitudinal myelitis associated with systemic lupus erythematosus Autoimmune Diseases public Spinal Cord Skin Diseases Nervous System Diseases 10 <p>Catastrophic longitudinal myelitis is an extremely rare neurologic manifestation of collagen vascular disease, described heretofore in 11 cases of SLE and 1 of Sjogren's Syndrome. This report documents markedly abnormal and worsening CSF findings on sequential CSF examinations over a period of three days (WBC >1500 cells/microL, >80% neutrophils, markedly elevated protein, and extremely low glucose levels) in the absence of infection. These abnormalities cleared rapidly with institution of immunosuppressive therapy so that a third CSF exam done within three days revealed almost complete normalization of CSF values. These findings suggest that in some cases of CLM a strong inflammatory component may be present, while in others, other pathogenic factors may predominate.<p> document-rn35384 10.1177/0961203307081846 38096 Lupus