Presentation Event Entity Entity Process Occurrent Occurrent 2025-05-07T04:25:11 RDF description of Mediators of weight loss in a multi-site randomized trial of a commercial weight loss program: the role of restraint and disinhibition [presentation] - http://repository.healthpartners.com/individual/document-rn30831 <p>Background: Successful weight loss and maintenance are challenging, underscoring the importance of<br>understanding mediators of short and longer-term success. Factors such as disinhibition and restraint<br>have been linked with unhealthy eating patterns, but also with successful weight control. Several<br>dimensions of restraint (i.e., flexible, rigid) and disinhibition (i.e., internal, external) have been identified.<br>These analyses examine whether subscale dimensions of restraint, disinhibition and hunger are mediators<br>of weight loss in women enrolled in a randomized clinical trial of a commercial weight loss program.<br>Method: Adult women (n=442) were randomized to one of three treatment arms, Jenny Craig (JC)<br>Centre-based, JC Direct (telephone-based), and usual care (UC) and are being followed for 24 months.<br>Sub-scales from the Eating Inventory, including Total, Internal and External Disinhibition, Total, Flexible,<br>and Rigid Restraint, and Total, Internal Locus and External Locus Hunger, are examined as mediators of<br>6- and 12-month weight change.<br>Results: Treatment group weight change differences were observed at 6 (JC=-8.9 kg (sd=5.0) vs UC=-3.1<br>kg (sd=5.0), p < .005) and 12 months (JC=-9.9 kg (sd=7.6) vs UC = -2.8 kg (sd=6.7), p < .0003). External<br>disinhibition and total, rigid, and flexible restraint were significant mediators of 6-month weight change.<br>Significant mediators of 12-month weight change included total (B=-0.77), flexible (B=-.346), and rigid<br>(B=-.086) restraint.<br>Conclusions: Results suggest that changes in external disinhibition, and multiple aspects of restraint are<br>important mediators of weight loss. Future analyses will examine the importance of these constructs for<br>long-term weight loss maintenance.<p> Randomized Controlled Trials 2022-02-21T22:48:57.408-06:00 public International Society of Behavioral Nutrition and Physical Activity (ISBNPA) Annual Connference presentation document-rn30831 34842 Weight Loss 20371 Obesity Mediators of weight loss in a multi-site randomized trial of a commercial weight loss program: the role of restraint and disinhibition [presentation]