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RDF description of Can paramedics accurately diagnose sepsis and severe sepsis in the field [abstract]? - http://repository.healthpartners.com/individual/document-rn26851
document-rn26851
Academic Emergency Medicine
2022-02-21T22:48:57.408-06:00
Can paramedics accurately diagnose sepsis and severe sepsis in the field [abstract]?
19125
public
Infectious Diseases
5 Suppl 1
<p>Background: Morbidity and mortality from sepsis and severe sepsis is a significant problem, with early recognition and treatment as areas of focus. Little work has been done to examine the ability of prehospital providers to identify sepsis and severe sepsis.<br>Objectives: Determine the accuracy of paramedic diagnosis of sepsis and severe sepsis using a diagnostic screening tool and point of care (POC) lactate measurement.<br>Methods: Following IRB approval, consented paramedics from a single, advanced life support (ALS) dual-role emergency medical services (EMS) agency underwent a one-hour training session on the universal criteria for sepsis diagnosis and the use of a POC lactate meter. Paramedics then screened every patient transported from three local nursing homes and assigned them a diagnosis of no sepsis, sepsis, or severe sepsis. The screening tool defined sepsis as an identified or suspected infection plus two of the following: temperature < 96.8 or >100.4F, heart rate > 90/min, respiratory rate > 20/min, or altered mental status. Severe sepsis was defined as meeting the sepsis criteria, as well as one of the following: mottled skin, capillary refill � 3 seconds, lactate > 2mmol/L, or abrupt changes in mental status. Patient charts were abstracted and a blinded physician assigned a final diagnosis to each patient. Sensitivity, specificity, negative and positive predictive values, and Cohen’s kappa were used to evaluate the agreement between the paramedic and physician diagnosis.<br>Results: One hundred and fifty-one patients were screened between October 2009 and February 2010, and 96 cases (64%) had both a paramedic and independent physician diagnosis assigned. Sensitivity, specificity, negative predictive value, and positive predictive value for sepsis diagnosis were 0.33 (95% CI 0.18, 0.53), 0.89 (95% CI 0.80, 0.94), 0.8 (95% CI 0.70, 0.87), and 0.50 (95% CI 0.28, 0.72). Sensitivity, specificity, negative predictive value, and positive predictive value for severe sepsis diagnosis were 0.20 (95% CI 0.05, 0.51), 0.94 (95% CI 0.87, 0.97), 0.91 (95% CI 0.83, 0.95), and 0.29 (95% CI 0.08, 0.64). The level of agreement between paramedic and physician diagnosis of sepsis and severe sepsis was low (kappa = 0.25 and 0.16, respectively).<br>Conclusion: Paramedics were able to accurately identify patients not experiencing sepsis or severe sepsis, but were not able to identify those with sepsis or severe sepsis with high sensitivity.<p>
32510
18
abstract
Emergency Medicine
Sensitivity and Specificity