Document Information Content Entity Continuant Continuant Abstract Entity Entity Generically Dependent Continuant 2025-05-06T10:45:09 RDF description of Impairment of carotid artery blood flow by supraglottic airway use in a swine model of cardiac arrest [abstract] - http://repository.healthpartners.com/individual/document-rn22751 2022-02-21T22:48:57.408-06:00 public Heart Diseases Animal Studies 17519 abstract 29478 <p>Introduction. Supraglottic airway devices (SGDs) are often used as an alternative to endotracheal tubes (ETTs) during cardiopulmonary resuscitation (CPR). SGDs can be inserted “blindly� and rapidly, without stopping compressions. These devices utilize pressurized balloons to direct air to the trachea and prevent esophageal insufflation.<br>Objective. We hypothesized that the use of an SGD would compress the carotid artery and decrease carotid blood flow (CBF) during CPR in pigs. <br>Methods.Ventricular fibrillation was induced in nine female pigs (32 ¡¾ 1 kg) anesthetized with isoflurane followed by 4 minutes without compressions. CPR was then performed continuously for three 6-minute epochs. During each epoch, an ETT was used for the first 3 minutes, followed by 3 minutes of each SGD (King LTS-D, LMA Flexible, or Combitube) in a random order. The primary endpoint was mean CBF (mL/min). Statistical comparisons among the four airway devices were performed by Wilcoxon rank test. Postmortem carotid arteriographies were performed with the SGDs in place. <br>Results. CBF (mean mL/min ¡¾ standard deviation) was significantly lower with each SGD (King [168 ¡¾ 42], LMA [106 ¡¾ 89], and Combitube [99 ¡¾ 128]) versus ETT (209 ¡¾ 134) (p < 0.05 for each SGD compared with ETT). Arteriograms showed that with each SGD there was compression of the internal and external carotid vessels. <br>Conclusions. The use of three different SGDs during CPR significantly decreased CBF in a porcine model of cardiac arrest. While limited to pigs, these observations may impact management decisions related to the type and duration of SGD use in humans undergoing CPR.<p> document-rn22751 Impairment of carotid artery blood flow by supraglottic airway use in a swine model of cardiac arrest [abstract] 16 Prehospital Emergency Care Resuscitation 1 Emergency Medicine