Document Information Content Entity Continuant Continuant Conference Poster Entity Entity Generically Dependent Continuant 2025-05-06T14:39:02 RDF description of Enhancing weight loss maintenance: 2 year results from the Keep It Off trial [poster] - http://repository.healthpartners.com/individual/document-rn22667 Comparative Studies Weight Loss Health Promotion Telephone 2022-02-21T22:48:57.408-06:00 Enhancing weight loss maintenance: 2 year results from the Keep It Off trial [poster] Obesity Randomized Controlled Trials 28836 public 17198 poster document-rn22667 Follow-Up Studies <p>Objective: The Keep It Off trial evaluated the efficacy of a phone- and mail-based weight loss maintenance intervention among adults who have recently lost weight.<br>Methods: Four hundred nineteen adults who had recently lost ? 10% of their body weight were randomized to the “Guided� or “Self-Directed� intervention. Guided participants received a 10 session workbook, 10 biweekly phone coaching calls, eight monthly and six bimonthly calls, and bimonthly weight graphs and tailored letters based on self-reported weights. Self-Directed participants received the same workbook and two coaching calls. Primary outcomes are weight change and maintenance (regain of < 2.5% of baseline body weight) at six, 12, 18, and 24 month follow-up. <br>Results: Mixed model repeated-measures analysis examining weight change revealed a significant time by treatment group interaction (F = 8.91, p < 0.035). Guided participants regained significantly less weight than Self-Directed participants at 12, 18, and 24 months. The odds of 24 month maintenance were 1.59 (95% CI: 1.04 - 2.41, p=0.03) times greater in the Guided than in the Self-Directed group. <br>Conclusions: A sustained, supportive phone- and mail-based intervention is effective in promoting weight loss maintenance relative to a brief intervention for participants who have recently lost weight.<p>