Article
Document
Academic Article
Information Content Entity
Continuant
Continuant
Journal Article
Entity
Entity
Generically Dependent Continuant
2025-05-10T20:13:22
RDF description of A comparison of peripheral and central human muscarinic cholinergic receptor affinities for psychotropic drugs - http://repository.healthpartners.com/individual/document-rn20394
2022-02-21T22:48:57.408-06:00
<p>A peripheral model offers a valuable research tool for the investigation of central cholinopathic disorders. The in vitro affinities of several psychotropic drugs for the muscarinic cholinergic binding sites of human caudate and erythrocyte were compared in competition with a tritiated antagonist (quinuclidinyl benzilate). The relative affinities of the drugs for both tissues were strikingly similar. Thus, the erythrocyte muscarinic receptor may represent an accessible in vitro assay for the characterization of central cholinopathic states.<p>
A comparison of peripheral and central human muscarinic cholinergic receptor affinities for psychotropic drugs
document-rn20394
public
5
Drugs and Drug Therapy
16671
17
Biological Psychiatry
Brain
27862