Article Document Information Content Entity Continuant Continuant Entity Entity Review Generically Dependent Continuant 2025-05-09T19:59:00 RDF description of Therapy in Huntington's disease: where are we [review]? - http://repository.healthpartners.com/individual/document-rn19822 12 Mental Disorders <p>As of 2012, almost 20 years after the discovery of the causative gene, clinical research has yet to find a disease-modifying treatment for Huntington's disease. However, both pharmacologic and nonpharmacologic therapies are available for many of the common symptoms of the disease. Recent studies of gene-positive patients in the prodromal, not clinically diagnosable, stages of the disease, are changing our perception of when the process of neurodegeneration begins. Once disease-modifying therapies become available, the approach to the diagnosis of Huntington's disease will likely shift from an examination-based clinical diagnosis, to one that includes a more complex combination of imaging, examination, and biomarker analysis.<p> Current Neurology and Neuroscience Reports 20616 13018 Animal Studies Dementia document-rn19822 public 2022-02-21T22:48:57.408-06:00 10.1007/s11910-012-0277-4 Nervous System Diseases 4 Therapy in Huntington's disease: where are we [review]? review