Article Document Academic Article Information Content Entity Continuant Continuant Journal Article Entity Entity Generically Dependent Continuant 2025-05-09T09:59:49 RDF description of Neurocognition in individuals co-infected with HIV and hepatitis C - http://repository.healthpartners.com/individual/document-rn18959 HIV-AIDS 14175 Journal of Addictive Diseases public Neurocognition in individuals co-infected with HIV and hepatitis C 2 Comorbidity document-rn18959 2022-02-21T22:48:57.408-06:00 <p>Due to similar routes of viral transmission, many individuals infected with the human immunodeficiency virus (HIV) are also infected with the hepatitis C virus (HCV). Each virus can cause cognitive compromise among mono-infected individuals; evidence is accumulating that HIV/HCV co-infection may have a particularly deleterious impact on cognition. We present neuropsychological data obtained from 118 HIV+ adults with advanced HIV disease, 35 of whom were co-infected with HCV, who completed a comprehensive neurocognitive evaluation. Rates of global cognitive impairment were higher among co-infected patients than among those with HIV alone (63% vs. 43%). Within the specific domains of learning and memory, co-infected individuals were significantly more likely to be impaired than were the HIV mono-infected participants. Finally, we discuss implications of these findings and potential future directions for research in this area.<p> 10.1300/J069v27n02_02 27 Dementia Brain Hepatitis 22930