Article Document Academic Article Information Content Entity Continuant Continuant Journal Article Entity Entity Generically Dependent Continuant 2025-05-09T04:25:37 RDF description of The effect of early intervention with sumatriptan tablets on migraine-associated productivity loss - http://repository.healthpartners.com/individual/document-rn18650 <p>OBJECTIVE: Impaired performance, which can considerably impact employee output, occurs when employees attempt to continue work with inadequate treatment while experiencing a migraine episode. This analysis examined productivity loss as a result of migraine after treatment with sumatriptan tablets and patients' usual non-triptan therapy when pain was mild (early intervention) versus when pain was moderate/severe. METHODS: The authors conducted a retrospective analysis of data on 6803 migraine days reported by 251 subjects who participated in a clinical trial. RESULTS: Although early intervention significantly reduced productivity loss compared with treatment when pain was moderate/severe for both sumatriptan and non-triptan therapy, productivity loss was consistently lower for sumatriptan than non-triptan therapy for all predose pain intensity levels. CONCLUSIONS: These findings suggest that the pharmaco-economic benefits of early intervention with sumatriptan tablets, like the clinical benefits, exceed those of delayed intervention.<p> 26018 Retrospective Studies Serotonin Receptor Agonists/*therapeutic use 15719 2022-02-21T22:48:57.408-06:00 Sumatriptan/*therapeutic use Pain/drug therapy Clinical Trials 47 Task Performance and Analysis The effect of early intervention with sumatriptan tablets on migraine-associated productivity loss document-rn18650 public Migraine Disorders/*drug therapy/physiopathology 11 Journal of Occupational and Environmental Medicine 10.1097/01.jom.0000174296.46911.79