Article Document Academic Article Information Content Entity Journal Article Continuant Continuant Entity Entity Generically Dependent Continuant 2025-05-06T23:36:23 RDF description of Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease - http://repository.healthpartners.com/individual/document-rn18490 *Polymorphism, Genetic Genetic Linkage 2022-02-21T22:48:57.408-06:00 Polymorphism, Single Nucleotide/genetics 60 7 Genotype Chromosomes, Human, Pair 8/genetics 12868 Risk Assessment Alleles Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease Parkinson Disease/*enzymology/*genetics <p>Recently, the authors demonstrated linkage in idiopathic PD to a region on chromosome 8p that contains the N-acetyltransferase genes, NAT1 and NAT2. The authors examined NAT1 and NAT2 for association with PD using family-based association methods and single nucleotide polymorphisms (SNPs). The authors did not find evidence for association with increased risk for PD between any individual NAT1 or NAT2 SNP or acetylation haplotype (N = 397 families, 1,580 individuals).<p> Isoenzymes/genetics 10.1212/01.wnl.0000055929.84668.9a 20316 Neurology Genetic Predisposition to Disease document-rn18490 Arylamine N-Acetyltransferase/*genetics public Aged Gene Frequency Haplotypes