Article Document Academic Article Information Content Entity Continuant Continuant Journal Article Entity Entity Generically Dependent Continuant 2025-05-06T21:52:41 RDF description of Ventilator-associated problems related to obstructive lung disease - http://repository.healthpartners.com/individual/document-rn18159 document-rn18159 Injuries 2022-02-21T22:48:57.408-06:00 Ventilator-associated problems related to obstructive lung disease 18032 Respiratory Care Respiration, Artificial 10.4187/respcare.02242 58 Critical Care <p>Relatively little attention has been directed toward damage inflicted upon the airway network that connects the alveoli, or toward the problems caused by invasive ventilation for patients with severe airflow obstruction. Mechanical ventilation with positive pressure can cause non-edematous barotrauma, inflict airway injury, and promote lung remodeling. Interactions between patient and ventilator, largely mediated through dynamic hyperinflation, include functional consequences for hemodynamics, respiratory muscle function, breathing work load, and patient-ventilator synchrony. Awareness of such associations not only helps to avoid complications during and after the critical phase of obstructive illness, but also opens a window to improved patient comfort and safety. The purpose of this review is to survey the range of structural damages and functional impairments that occur in an "obstructive" context.<p> 6 11726 Lung Diseases public Adverse Effects