Document Information Content Entity Continuant Continuant Conference Poster Entity Entity Generically Dependent Continuant 2025-05-06T16:17:18 RDF description of Comparing patch vs.pen bolus insulin delivery in type 2 diabetes using continuous glucose monitoring metrics and profiles [poster] - http://repository.healthpartners.com/individual/document-rn12083 Diabetes <p>Patients with T2D (N=97, A1c �7.5% on basal insulin) used DexCom G4 CGM in a substudy of a large RCT (N=278) to evaluate bolus insulin delivery by patch (Calibra Medical) vs. pen (Novolog Flexpen®) using an SMBG-based titration algorithm. There was a significant improvement (p<0.0001) in A1c and all CGM metrics at week 24, but no difference between groups (Table). CGM profiles (Figure) demonstrate it is possible to optimize basal-bolus therapy, dramatically increasing time-in-target range (70-180 mg/dL) with minimal significant hypoglycemia (<54 mg/dL) while achieving a flat bedtime to AM glucose profile. This is one of the first trials to clearly demonstrate how using CGM metrics and CGM profiles in T2D can provide a more clinically relevant comparison of different approaches to optimizing glucose management.<p> 22912 Drugs and Drug Therapy Blood poster public 14166 2022-02-21T22:48:57.408-06:00 Comparing patch vs.pen bolus insulin delivery in type 2 diabetes using continuous glucose monitoring metrics and profiles [poster] Monitoring, Physiologic document-rn12083