We have previously shown that higher intake of cruciferous vegetables is inversely associated with carotid artery intima-media thickness. To further test the hypothesis that an increased consumption of cruciferous vegetables is associated with reduced indicators of structural vascular disease in other areas of the vascular tree, we aimed to investigate the cross-sectional association between cruciferous vegetable intake and extensive calcification in the abdominal aorta. Dietary intake was assessed, using a FFQ, in 684 older women from the Calcium Intake Fracture Outcome Study. Cruciferous vegetables included cabbage, Brussels sprouts, cauliflower and broccoli. Abdominal aortic calcification (AAC) was scored using the Kauppila AAC24 scale on dual-energy X-ray absorptiometry lateral spine images and was categorised as 'not extensive' (0-5) or 'extensive' (鈮�6). Mean age was 74路9 (sd 2路6) years, median cruciferous vegetable intake was 28路2 (interquartile range 15路0-44路7) g/d and 128/684 (18路7 %) women had extensive AAC scores. Those with higher intakes of cruciferous vegetables (>44路6 g/d) were associated with a 46 % lower odds of having extensive AAC in comparison with those with lower intakes (<15路0 g/d) after adjustment for lifestyle, dietary and CVD risk factors (ORQ4 v. Q1 0路54, 95 % CI 0路30, 0路97, P = 0路036). Total vegetable intake and each of the other vegetable types were not related to extensive AAC (P > 0路05 for all). This study strengthens the hypothesis that higher intake of cruciferous vegetables may protect against vascular calcification.
